Leukemias
| Features of CLL | Common features | Features of CML |
| Age >50 | Age >60 | |
| Lymphadenopathy | Splenomegaly | |
| Commonest leukemia in US | Converts to blastic phase | |
| Pancytopenia | ||
| Immune dyscrasias | ||
| Bone marrow exam | ||
| Cytogenetics in case of difficulty with diagnosis | Philadelphia chromosome (9-22 translocation) | |
| Neutrophil alkaline phosphatase level = 0 or decreased ( in leukemoid reaction) | ||
| Treated with BMT in young or alfa interferon in elderly without a donor or hydroxyurea | ||
| Try to keep cells below 30 K |