1. ^{The risk of fulminant hepatitis with Hepatitis B virus is high, almost 40%}
2. ^{The risk of persistent hepatitis viremia is about 25% in immunocompetent and 50% in immunocompromised}
3. ^{Chronic hepatitis B infection confers a substantial risk of hepatocellular carcinoma up to 40%}
4. ^{Hepatitis B is an RNA virus}

Answer: The answer is (c). The risk of fulminant hepatitis with Hepatitis B is quite rare and is about 1%. The cases of fulminant hepatitis have about 60% mortality. Persistent Hepatitis B occurs in 1-2% of immunocompetent hosts and about 5% in the immunocompromised. Hepatitis B is a DNA virus. Chronic Hepatitis B is associated with a substantial risk of hepatocellular carcinoma.

1. ^{The vaccines are recombinant human vaccines}
2. ^{Universal vaccination for infants and children is recommended}
3. ^{Those who do not seroconvert after complete vaccination can be protected by 3 additional doses of vaccine}
4. ^{For checking serological status, the serum HBV titers have to be assayed.}

Answer: The answer is (d). Hepatitis B vaccine is a recombinant human vaccine. Universal vaccination is recommended for children. The non-responders to hepatitis B vaccine can be protected by additional three doses of the vaccine. For checking the serological status, the hepatitis B surface antigen needs to be assayed.