Uric acid nephropathy

^{Which of the following statements about uric acid nephropathy is false?}

^{^{It can occur as a part of the tumor lysis syndrome}
^{It is common in patients undergoing anti-cancer chemotherapy}
^{Acidifying the urine is useful in managing this condition}
^{It can be prevented by starting the patient on allopurinol before starting the
chemotherapy}

Answer: The answer is (c). Uric acid nephropathy occurs due to production of excess
uric acid during excess cell kill. This occurs as a part of tumor lysis syndrome,
anti-cancer chemotherapy. Adding allopurinol to the treatment before starting the
anti-cancer chemotherapy can prevent it. Forced alkaline diuresis can help to prevent the
dangerous effects of uric acid on the kidney.}